The vision, goals, objectives, and other components of the HIV Plan were developed and approved by a dedicated Steering Committee, composed of subject matter experts from across the federal government, with input from numerous and varied stakeholders in the field. The HIV Plan is designed to be accessible to and useful for a broad audience, including people working in public health, health care, government, community-based organizations, research, and academia. It serves as a roadmap for stakeholders from all sectors of society to guide the development of policies, services, programs, initiatives, and other actions to achieve the nation’s vision of ending the HIV epidemic by 2030. While not every objective or strategy will speak to or be actionable by all readers, the intent is that individuals and organizations from all sectors of society can find opportunities where they can support necessary scale-up, expansion, and refinement efforts. Entities vital to ending the HIV epidemic in this country are located in rural or low to moderate HIV prevalence jurisdictions as well as higher prevalence ones and include community-based, faith-focused, and advocacy organizations; governmental public health; mental health and substance abuse treatment services; the criminal justice system; and providers of housing, food and nutrition, education, and employment services.